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Rachel Matt Graduate Student Stanford University Stanford, California Select a Country Website |
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EPR Techniques: | cw EPR, DEER / PELDOR, pulse EPR |
Research Areas: | drug development, membrane proteins |
Personal Statement: | Allosteric drugs have the ability to fine-tune cellular response and direct cell signaling towards a particular pathway for the largest class of druggable proteins, G protein coupled receptors (GPCRs). I use continuous wave and DEER EPR spectroscopies to study GPCRs in the presence of allosteric ligands, to identify the mechanism of the allosteric response, and inform future rational drug design. |